MicrobiologybioRxiv
In Vivo Dual RNA-Seq Analysis Reveals the Basis for Differential Tissue Tropism of Clinical Isolates of Streptococcus pneumoniae
V. Minhas, R. Aprianto, L. J. McAllister…·C. Trappetti
This study uses dual RNA-seq to show how a single SNP in Streptococcus pneumoniae affects bacterial and host gene expression, leading to differential tissue tropism and disease outcomes.
DOI 10.1038/s42003-020-1018-x