mRNA structure determines specificity of a polyQ-driven phase separation
E. M. Langdon, Y. Qiu, A. Ghanbari Niaki, G. McLaughlin, C. Weidmann, T. Gerbich, J. A. Smith, J. M. Crutchley, C. M. Termini, K. M. Weeks, S. Myong, A. Gladfelter
The paper shows that mRNA secondary structures determine RNA-RNA interactions that influence phase separation and compartment identity.
bioRxiv · Mar 7, 2018Cell Biology