Nifedipine Modulated Renal Lipogenesis via AMPK-SREBP Transcriptional Pathways
Y.-C. Lin, M.-S. Wu, C.-R. Chen, C.-Y. Chen, C.-J. Chen, K.-C. Chen, C.-C. Peng
This study shows nifedipine induces renal lipotoxicity by activating the AMPK-SREBP pathway, leading to lipid accumulation and renal damage.
bioRxiv · Dec 4, 2018 · PreprintBiochemistry