NK cell metabolic adaptation to infection promotes survival and viral clearance.
F. Victorino, T. Bigley, E. Park, C.-H. Yao, J. Benoit, L.-P. Yang, S. J. Piersma, E. J. Lauron, R. M. Davidson, G. J. Patti, W. M. Yokoyama
This study shows HIF-1 is essential for NK cell survival and viral clearance during MCMV infection by regulating metabolism and preventing apoptosis.
bioRxiv · Mar 17, 2021Immunology