C.-j. Lee

Intermolecular interactions between cysteine and aromatic amino acids with phenyl moiety in the DNA-binding domain of heat shock factor 1 regulate thermal stress-induced trimerization.

This study identifies that the amino acid at residue 103 of HSF1 regulates trimer formation temperature through intermolecular interactions with aromatic residues.

Single-cell microencapsulation improves lung retention of endothelial colony forming cells after intravascular delivery and unmasks therapeutic benefit in severe pulmonary arterial hypertension

This study shows that microencapsulation of endothelial colony forming cells (ECFCs) improves their lung retention and therapeutic efficacy in a rat model of pulmonary arterial hypertension.