Can motional dynamics account for the cytotoxicity of beta amyloid oligomers?
C.-T. Yeh, H.-W. Chang, W.-H. Hsu, S.-J. Huang, M.-H. Wu, L.-H. Tu, M.-C. Lee, C. C. J. Chan
This study investigates how the size and motional dynamics of beta amyloid oligomers relate to their cytotoxicity, finding that smaller oligomers are more toxic due to increased motion of charged residues.
bioRxiv · May 4, 2023 · PreprintBiophysics