Author

Cai Lei

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Chao LiuiD· 1 shared Eugene V. KooniniD· 1 shared Feiyue ChengiD· 1 shared Gabrielle Reilly· 1 shared Guangyi Liang· 1 shared Jiachen YaoiD· 1 shared Jing Xu· 1 shared Jun DuiD· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperMicrobiology

Chao LiuORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Phage CRISPR-like regulatory RNAs silence multilayered bacterial immune systems

Chao Liu, Zhihua Li, Rui Wang, Wenhe Wang, Jiachen Yao, Junyuan Xue, Xiaoyu Du, Jing Xu, Guangyi Liang, Feiyue Cheng, Xiaoyu Du, Linlin Guan, Mario Rodríguez Mestre, Jun Du, Cai Lei, , Ming Li

The paper identifies viral crlRNAs that suppress bacterial immunity by reprogramming Cas proteins and demonstrates their potential for mammalian genome editing.

bioRxiv · Oct 29, 2024 · PreprintMicrobiology

Sorting Nexin 27 (SNX27): A Novel Regulator of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Trafficking

Mark I. McDermott, William R. Thelin, Yun Chen, Patrick T. Lyons, Gabrielle Reilly, Martina Gentzsch, Cai Lei, Wanjin Hong, M. Jackson Stutts, Martin P. Playford, Vytas A. Bankaitis

This study identifies SNX27 as a novel regulator of CFTR trafficking, showing it facilitates CFTR recycling and prevents degradation in airway epithelial cells.

bioRxiv · Apr 19, 2018 · PreprintCell Biology