Molecular BiologyCell DiscoveryPeer-reviewed
Mechanisms of ligand recognition and activation of melanin-concentrating hormone receptors
He Qian, Qingning Yuan, Hong Shan…·Lihua Zhao
This study presents cryo-EM structures of MCH-activated MCHR1 and MCHR2 with G-proteins, revealing ligand recognition mechanisms and activation pathways.
14 citations