Cancer BiologybioRxivPreprint
Tumor intrinsic regulation of PD-L1 and of interferon Type I via an SLC25A1-driven mitochondrial pathway, influences the anti-tumor immune response
Rami Mosaoa, Maha Moussa, Aditya Kavuturu…·Maria Laura Avantaggiati
This study identifies SLC25A1 as a regulator of PD-L1 and type I interferon signaling via a mitochondrial pathway, influencing tumor immune response and immunotherapy efficacy.
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