Author

Chao Dong

Central South University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Genomics· 1 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:rat· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:CRISPR screen· 1

Frequent Co-Authors

Alexandra BraduiD· 1 shared Benan N. NalbantiD· 1 shared Caleb A. LareauiD· 1 shared Carl M. McCormickiD· 1 shared Erin M. CummingiD· 1 shared He Huang· 1 shared Hui‐Chun HuangiD· 1 shared Isabella MascioiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperGenomics

Alexandra BraduORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Genome-wide single-cell perturbation screens with VIPerturb-seq

Alexandra Bradu, John D. Blair, Erin M. Cumming, Isabella Mascio, Junsuk Lee, Carl M. McCormick, Radhika Rathi, Benan N. Nalbant, Chao Dong, Caleb A. Lareau, Rahul Satija

VIPerturb-seq enables genome-wide CRISPR perturbation screens using probe-based detection, improving throughput and efficiency for single-cell analysis.

bioRxiv · Aug 20, 2026 · PreprintGenomics

Construction of a GnRH mRNA Immunocastration Vaccine and Evaluation of Its Immunogenicity and Safety in Mice and Cats

Y. Chen, Chao Dong, Wenqian Yan, Yakun Liu, Jixiang Sun, Mingshuo Ji, Jiahan Gang, Jiaqi Nie, Xinhao Zhang, He Huang, Yongfei Zhou

This paper develops a GnRH mRNA vaccine using pLS nanoparticles and evaluates its immunogenicity, reproductive suppression, and safety in mice and cats.

bioRxiv · Mar 26, 2026 · PreprintImmunology

Hepatic Arterial Flow-Induced Portal Tract Fibrosis in Portal Hypertension: The Role of VCAM-1 and Osteopontin-Expressing Macrophages

Ruixue Ma, Li Gong, Chao Dong, Teruo Utsumi, Jiewen Qi, Zhen W. Zhuang, Xuchen Zhang, Yilin Yang, Matthew J. McConnell, Hui‐Chun Huang, Yasuko Iwakiri

This study shows that increased VCAM-1 in hepatic artery endothelial cells and portal fibroblasts recruits Spp1+ macrophages, driving fibrosis in portal hypertension.

Cellular and Molecular Gastroenterology and Hepatology · Jan 1, 2026Peer-reviewedPathology