Author

Chenchen Xu

Chinese University of Hong Kong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Research Focus:protein folding & dynamics· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Xin WangiD· 3 shared Felicia JiangiD· 2 shared Feng Liang· 2 shared Jia XuiD· 2 shared Minghao XuiD· 2 shared Runhao Zhao· 2 shared Taoyong CuiiD· 2 shared Tianli LuoiD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Xin WangORCID

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3 papers

Recent·Most cited

FFPERescuer: deep unsupervised domain adaptation for the reconstruction of gene expression profiles derived from formalin-fixed paraffin-embedded samples

Lingli He, Kai Song, Ying Li, Yujuan Dong, Cherry Y N Wong, Lin Qi, Xianrui Zhang, Kristiaan Lenos, Tim R. de Back, Clara C. Elbers, Chenchen Xu, Royce Man Hin Leung, Renfu Deng, Yinghan Zhang, Sitan Qiao, , Xin Wang

FFPERescuer uses deep learning to improve gene expression reconstruction from degraded FFPE samples, achieving high accuracy and enhancing cancer subtyping.

bioRxiv · Sep 8, 2026 · PreprintBioinformatics

Alternative splicing expands and remodels the breast cancer proteoform landscape

Tao Jiang, Dengwang Chen, Xiangeng Wang, Hao Hao, Yinghan Zhang, Runhao Zhao, Feng Liang, Taoyong Cui, Zhenchao Tang, Tianli Luo, Yi Shuai, Minghao Xu, Chenchen Xu, Jia Xu, Wentao Zhang, , Xin Wang

The paper develops 3DisoGalaxy to study alternative splicing in breast cancer, finding that many transcripts produce translation-supported proteins and that functional divergence is concentrated in specific regions.

bioRxiv · Aug 26, 2026 · PreprintCancer Biology

Structure-aware protein function prediction at isoform resolution

Felicia Jiang, Runhao Zhao, Feng Liang, Xiang Zhao, Taoyong Cui, Zhenchao Tang, Y S Zhang, Danyu Chen, minghao Xu, Yi Shuai, Tianli Luo, Xiangeng Wang, Chenchen Xu, Ziwei Wang, Weixin Zeng, , Xin Wang

This study develops a framework for predicting protein function and domain annotation at isoform resolution using structural and sequence data, showing strong performance in benchmark tests and capturing domain changes across isoforms.

bioRxiv · Jun 7, 2026 · PreprintCancer Biology