Author

Cheng Fang

Boston UniversityPrimary ORCID profile (0009-0003-3545-0116 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Cheng FangiD1 paper · Southern University of Science and Technology

Biology Disciplines

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Bioinformatics· 1 Microbiology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Adam Thomas LabadorfiD· 1 shared Aihua ZhaoiD· 1 shared Akshat Shirish ZalteiD· 1 shared Alan C. ChengiD· 1 shared Andreas BenderiD· 1 shared Andrew EmiliiD· 1 shared Aravind SundaravadiveluiD· 1 shared Arijit PatraiD· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperNeuroscience

Adam Thomas LabadorfORCID

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3 papers

Recent·Most cited

Model Validation Protocols for Machine Learning in Small Molecule Drug Discovery

Srijit Seal, Akshat Shirish Zalte, David Alencar Araripe, Renan Augusto Gomes, Deepa Korani, Mrinal Shekhar, Vishal B. Siramshetty, Arijit Patra, Zhongyu Mou, Xiang Yu, Daniel Kühn, Nils Weskamp, Jeremy R. Ash, Alan C. Cheng, Cheng Fang, , Cas Wognum

The paper presents a model validation framework for molecular property prediction models in drug discovery, revealing four failure modes and showing that common evaluation protocols overestimate performance.

bioRxiv · Aug 24, 2026 · PreprintBioinformatics

Chemo-omic pipeline enables discovery of prion synaptotoxic pathways and inhibitory drugs

Nhat T. T. Le, Robert C.C. Mercer, Cheng Fang, Aravind Sundaravadivelu, Adam Thomas Labadorf, Weiwei Lin, Julian Kwan, Benjamin C. Blum, Andrew Emili, David A. Harris

The paper identifies prion synaptotoxic pathways and inhibitory drugs using phosphoproteomic and transcriptomic data from prion-treated neurons.

PLoS Pathogens · Jun 18, 2026Peer-reviewedNeuroscience

Flavor compounds in fermented Chinese alcoholic beverage alter gut microbiota and attenuate ethanol-induced liver

Cheng Fang, Hai Du, Zheng Xiaojiao, Aihua Zhao, Wei Jia, Yan Xu

This study shows that Chinese Baijiu reduces liver injury in mice by altering gut microbiota and metabolome compared to pure ethanol.

bioRxiv · Oct 8, 2018 · PreprintMicrobiology