Systems BiologyNature CommunicationsPeer-reviewed
Core elements play distinct roles in promoter birth and transcriptional regulation
Syue-Ting Antony Kuo, Wei-Yi Shen, Shinn-Juh Lai…·Hsin-Hung David Chou
The paper investigates the roles of core promoter elements -35 and -10 in Escherichia coli, showing -10 is essential for promoter evolution while -35 influences gene regulation through interactions with transcription factors.
DOI 10.1038/s41467-026-75686-2