In vivo single-cell CRISPR screening for microproteins identifies a critical ribosomal component
Fabiola Valdivia-Francia, Umesh Ghoshdastider, Peter F. Renz, Daniel Spies, Mark Ormiston, Katie Hyams, Chenke Shi, Clara Duré, Merve Yiğit, David Taborsky, Ameya Khandekar, Ramona Weber, Homare Yamahachi, Stephanie J. Ellis, Ataman Sendoel
The paper uses in vivo single-cell CRISPR screening in mouse epidermis to identify a microprotein critical for ribosome function and cell proliferation.
bioRxiv · Mar 17, 2025 · PreprintGenetics