Molecular BiologybioRxivPreprint
Amyloid fibril polymorphism in the heart and the liver of an ATTR amyloidosis patient with polyneuropathy attributed to the ATTRv-V122Δ variant
Yasmin Ahmed, Binh An Nguyen, Candace Kelly…·Lorena Saelices
The paper uses cryo-electron microscopy to characterize amyloid fibrils from the heart and liver of an ATTRv amyloidosis patient with the V122Δ mutation, finding structural polymorphism linked to polyneuropathy.
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