Author

Christian Markopoulos

Rockefeller University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Albert Ruzo· 1 shared Ali H. BrivanlouiD· 1 shared Anna YoneyiD· 1 shared Fred EtociD· 1 shared Jakob Johannes MetzgeriD· 1 shared Shu LiiD· 1 shared Szilvia GalgocziiD· 1 shared Tien Phan-Everson· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperDevelopmental Biology

Albert Ruzo

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1 paper

Recent·Most cited

Huntingtin CAG expansion impairs germ layer patterning in synthetic human gastruloids through polarity defects.

Szilvia Galgoczi, Albert Ruzo, Christian Markopoulos, Anna Yoney, Tien Phan-Everson, Shu Li, Tomomi Haremaki, Jakob Johannes Metzger, Fred Etoc, Ali H. Brivanlou

This study shows that HTT-CAG expansion in human gastruloids causes ectodermal compartment reduction and altered TGFβ signaling due to polarity defects, indicating early developmental HD effects.

Development · Oct 1, 2021Peer-reviewedDevelopmental Biology