Cancer BiologybioRxivPreprint
Nuclear lamin A/C phosphorylation by loss of Androgen Receptor is a global determinant of cancer-associated fibroblast activation.
Soumitra Ghosh, Jovan Isma, Luigi Mazzeo…·G. Paolo Dotto
This study shows that loss of androgen receptor increases lamin A/C phosphorylation, driving cancer-associated fibroblast activation through transcriptional changes.
DOI 10.1101/2023.06.28.546870