Airway IRF7hi versus IRF7lo molecular response patterns determine clinical phenotypes in children with acute wheezing
Siew-Kim Khoo, James Read, Kimberley Franks, Guicheng Zhang, Joelene Bizzintino, Laura Coleman, Christopher McCrae, Lisa Öberg, Niamh Troy, Franciska Prastanti, Janet Everard, Stephen Oo, Meredith L Borland, Rose A Maciewicz, Peter N Le Souëf, , Anthony Bosco
The paper identifies IRF7hi and IRF7lo molecular phenotypes in children with acute wheezing, showing distinct clinical outcomes related to symptom duration and hospital admission.
bioRxiv · Nov 21, 2017 · PreprintCell Biology