COPD lungs show an attached stratified mucus layer resembling the protective colonic mucus
Joan Antoni Fernández-Blanco, Liisa Arike, Anna Ermund, Dalia Fakih, Ana M. Rodríguez-Piñeiro, Beatriz Martínez-Abad, Elin Skansebo, Sonya Jackson, James Root, Dave Singh, Christopher McCrae, Christopher M. Evans, Annika Åstrand, Gunnar C. Hansson
The paper compares mucus composition and structure in COPD, CF, and colonic mucus, finding similarities in proteomes and a protective attached mucus layer in the lungs.
bioRxiv · Oct 19, 2017 · PreprintPhysiology