QuadCleave: Enzymatic cleavage and analysis of DNA G-quadruplexes.
Rachael D. Baker, Alaina Hrysikos, Olivia Lewis…·Bidyut K. Mohanty
QuadCleave provides an inexpensive, efficient method to validate G4-forming sequences and assess their repeat counts using two enzymes, with application to C9ORF72 in ALS and FTD.