Molecular BiologybioRxivPreprint
Evaluation of K-Ras4B dimer interfaces and the role of Raf effectors
Alexios Chatzigoulas, Ioannis Andreadelis, Stefan Doerr…·Zoe Cournia
This study evaluates K-Ras4B dimer interfaces and finds that Raf effectors stabilize dimers on the membrane, identifies a dynamic water channel, and suggests modulating membrane interactions as a potential therapeutic strategy.
DOI 10.1101/2022.10.04.510804