Cell BiologybioRxivPreprint
DNA replication stress redistributes the histone methyltransferase G9a and activates lineage-specific gene expression
Gillian E. Oaks, Brian T. Do, Emma M Jakubicka…·Matthew G. Vander Heiden
The paper shows DNA replication stress redistributes G9a to stalled forks, activates gamma-globin genes, and explains how hydroxyurea increases fetal hemoglobin in sickle cell anemia.