NeurosciencebioRxivPreprint
Gene-corrected Parkinson's disease neurons show the A30P alpha-synuclein point mutation leads to reduced neuronal branching and function
Peter A. Barbuti, Bruno F. R. Santos, Paul M. A. Antony…·Rejko Krüger
This study shows that the A30P alpha-synuclein mutation in Parkinson's disease neurons reduces branching and function, with mitochondrial dysfunction and susceptibility to Rotenone.