Claudia Cuevas

The paper characterizes gene expression responses to biomechanical strain in an in vitro model of osteoarthritis using iPSC-chondrocytes and identifies inter-individual expression differences in response to mechanical strain.

This study identifies divergence in alternative polyadenylation (APA) between humans and chimpanzees as a contributor to gene regulatory differences, particularly in protein expression.

This study compares gene expression variability and eQTLs in humans and chimpanzees, finding shared genetic and non-genetic determinants of inter-individual expression differences.

The paper compares gene expression and DNA methylation across tissues and species in primates, finding that only 7-11% of inter-species expression differences are explained by methylation, with higher explanation in tissue-specific genes.