Cancer BiologybioRxivPreprint
ASS1 deficiency defines a therapeutic vulnerability in Philadelphia chromosome-positive acute lymphoblastic leukaemia
Michael James Austin, Shruti Patel, Ronas Taner Kesmez…·Bela G. Patel
This study identifies ASS1 deficiency as a therapeutic target in Ph+ ALL, showing arginine deprivation induces apoptosis and overcomes TKI resistance.
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