Systems BiologyNature CommunicationsPeer-reviewed
A genome-scale metabolic model of Saccharomyces cerevisiae that integrates expression constraints and reaction thermodynamics
Omid Oftadeh, Pierre Salvy, María Masid…·Vassily Hatzimanikatis A
This paper develops yETFL, an extended ME-model for Saccharomyces cerevisiae that integrates expression constraints and reaction thermodynamics, demonstrating its predictive ability for growth rate, essential genes, and overflow metabolism.
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