Tuba activates Cdc42 during neuronal polarization downstream of the small GTPase Rab8a
P. J. Urrutia, F. Bodaleo, D. A. Borquez, V. Rozes-Salvador, C. Villablanca, C. Conde, M. Fukuda, C. Gonzalez-Billault
This study identifies Tuba as a GEF that links Rab8a and Cdc42 in neuronal polarization, showing a feedback loop essential for axon specification.
bioRxiv · Dec 16, 2019Cell Biology