Venturicidin A affects the mitochondrial membrane potential and induces kDNA loss in Trypanosoma brucei
D. A. Hauser, M. Kaiser, P. Mäser, A. Albisetti
This study shows venturicidin A targets ATP synthase in Trypanosoma brucei, causing mitochondrial membrane potential loss and kDNA loss, suggesting it as a potential antitrypanosomatid drug.
bioRxiv · Jan 12, 2024 · PreprintMicrobiology