High-throughput microfluidic micropipette aspiration device to probe time-scale dependent nuclear mechanics in intact cells
P. Davidson, G. Fedorchak, S. Mondesert-Deveraux, E. Bell, P. Isermann, D. Aubry, R. Allena, J. Lammerding
This paper introduces a microfluidic device for high-throughput measurement of time-dependent nuclear mechanics in cells, showing that lamin A/C loss increases nuclear deformability.
bioRxiv · May 20, 2019Biophysics