P. Davidson

State diagrams of type I collagen for the rational design of biomimetic materials

This paper establishes state diagrams for type I collagen to understand fibrillogenesis conditions and optimize biomimetic material production.

The histone lysine demethylase KDM5C fine-tunes gene expression to regulate dendritic cell heterogeneity and function

This study shows KDM5C regulates dendritic cell (DC) heterogeneity and function by modulating epigenetic programming and subset balance, affecting immune responses to infection.

A versatile high-throughput assay based on 3D ring-shaped cardiac tissues generated from human induced pluripotent stem cell derived cardiomyocytes

The paper develops a high-throughput 3D cardiac tissue assay using human iPSC-derived cardiomyocytes and fibroblasts to study mechanical and drug responses.

Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer

This study shows that low lamin A levels in breast cancer cells increase nuclear deformability and metastatic capacity, with lower lamin A levels linked to poorer disease-free survival in human tumors.

High-throughput microfluidic micropipette aspiration device to probe time-scale dependent nuclear mechanics in intact cells

This paper introduces a microfluidic device for high-throughput measurement of time-dependent nuclear mechanics in cells, showing that lamin A/C loss increases nuclear deformability.