Challenges of γ9δ2TCR affinity maturation when using phage display
L. Kramer, M. Demuysere, E. van Diest, D. Beringer, J. Kuball
This study attempts to enhance the functional avidity of γ9δ2TCR through affinity maturation using phage display but fails due to instability of the scTCR format in bacterial expression.
bioRxiv · May 20, 2021 · PreprintImmunology