Author

E. van Diest

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

J. Kuball· 2 shared D. Beringer· 1 shared D. X. Beringer· 1 shared I. Johanna· 1 shared L. Kramer· 1 shared M. Demuysere· 1 shared P. Hernandez-Lopez· 1 shared S. Heijhuurs· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

J. Kuball

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2 papers

Recent·Most cited

Challenges of γ9δ2TCR affinity maturation when using phage display

L. Kramer, M. Demuysere, E. van Diest, D. Beringer, J. Kuball

This study attempts to enhance the functional avidity of γ9δ2TCR through affinity maturation using phage display but fails due to instability of the scTCR format in bacterial expression.

bioRxiv · May 20, 2021 · PreprintImmunology

Enhancing cancer targeting of γ9δ2TCR through modified NKG2D co-stimulation

P. Hernandez-Lopez, E. van Diest, I. Johanna, S. Heijhuurs, T. Straetemans, Z. Sebestyen, D. X. Beringer, J. Kuball

This paper improves the antitumor activity of TEG001 by co-expressing NKG2D-based chimeric co-receptors with the {gamma}{delta}TCR-Cl5.

bioRxiv · Jan 6, 2021 · PreprintImmunology