Author

D. Bernard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Nkansah· 2 shared C. MACHON· 2 shared E. Cosgriff-Hernandez· 2 shared J. GUITTON· 2 shared M. Razavi· 2 shared N. MARTIN· 2 shared A. CHOQUET· 1 shared A. D. Post· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBioengineering

A. Nkansah

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A Comprehensive Framework for Spatio-Temporal Analysis of DNA Damage Foci in Tumor Spheroids.

M. CAZALES, T. LIU, D. Bernard, D. JULLIEN, C. LORENZO

This paper develops a semi-automated image analysis framework to quantify spatiotemporal DNA damage foci in live tumor spheroids using live imaging and fluorescent sensors.

bioRxiv · Jul 19, 2024Cell Biology

Translational control of cell plasticity drives 5-FU tolerance

M. CHALABI-DCHAR, O. VILLERONCE, J. RIPOLL, A. VINCENT, T. FENOUIL, R. KHOUEIRY, J. KUCHARCZAK, L. JENTSCHEL, F. CATEZ, A. M. Vigneron, J. TREGUIER, C. MANDIER, C. BOUCLIER, J. VITRE, L. LAGERQVIST, , J.-J. DIAZ

The paper shows 5-FU induces translational reprogramming in colorectal cancer cells, enhancing drug tolerance through pro-tumoral gene expression and IL-8 overexpression.

bioRxiv · Jul 3, 2024 · PreprintCancer Biology

Eliminating steam pops and improving lesion safety in atrial ablation with conductive hydrogels

A. D. Post, L. Jaworski, D. Bernard, D. Bashe, S. Goal, H. D. Zhang, A. Nkansah, E. Cosgriff-Hernandez, M. Razavi

This study evaluates conductive hydrogels as a medium for RF ablation in atrial fibrillation, showing reduced steam pops, improved lesion homogeneity, and better esophageal protection.

bioRxiv · Oct 3, 2023 · PreprintBioengineering

Towards prevention of re-entrant arrhythmias: Injectable hydrogel electrodes enable direct capture of previously inaccessible cardiac tissues

G. Rodriguez-Rivera, A. Post, M. John, S. Buchan, M. Wancura, M. Chwatko, C. Waldron, A. Nkansah, D. Bernard, N. Kalkunte, J. Zoldan, M. Arseneault, M. Razavi, E. Cosgriff-Hernandez

This paper develops injectable hydrogel electrodes that can pace previously inaccessible mid-myocardial tissue, mimicking physiologic conduction and offering a potential alternative to current arrhythmia treatments.

bioRxiv · Nov 3, 2021 · PreprintBioengineering

Cholesterol biosynthetic pathway induces cellular senescence through ERRa

D. V. Ziegler, M. Vernier, J. Czarnecka-Herok, C. Scholtes, C. Machon, J. Guitton, J. Rieusset, V. Giguere, N. Martin, D. Bernard

This study shows the mevalonate pathway promotes cellular senescence via ERRα, causing mitochondrial dysfunction, ROS, DNA damage, and p53-dependent senescence.

bioRxiv · Oct 20, 2021Cell Biology