Disentangling the Innate Immune Responses of Intestinal Epithelial Cells and Lamina Propria Cells to Salmonella Typhimurium Infection in Chickens
K. Sutton, T. Nash, S. Sives, D. Borowska, J. Mitchell, P. Vohra, M. Stevens, L. Vervelde
This study compares innate immune responses in 2D and 3D chicken enteroids infected with Salmonella Typhimurium, showing that 3D models better mimic in vivo responses due to the presence of lamina propria cells.
bioRxiv · Jul 14, 2023 · PreprintImmunology