Author

D. Brena

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:behavioral assay· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Villanueva· 2 shared C. Martinez-Fernandez· 2 shared E. Nadal· 2 shared J. Ceron· 2 shared S. Honnen· 2 shared A. Miranda-Vizuete· 1 shared F. J. Garcia-Rodriguez· 1 shared M. Bergamino· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCell Biology

A. Villanueva

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Author profile →

2 papers

Recent·Most cited

Insights into cisplatin-induced neurotoxicity and mitochondrial dysfunction in Caenorhabditis elegans

C. Martinez-Fernandez, M. Bergamino, D. Brena, N. Ventura, S. Honnen, A. Villanueva, E. Nadal, J. Ceron

This study investigates cisplatin-induced neurotoxicity and mitochondrial dysfunction in C. elegans using genetic, biochemical, and behavioral assays.

bioRxiv · Jun 3, 2021Cell Biology

Genetic and cellular sensitivity of Caenorhabditis elegans to the chemotherapeutic agent cisplatin

F. J. Garcia-Rodriguez, C. Martinez-Fernandez, D. Brena, E. Nadal, M. Boxem, S. Honnen, A. Miranda-Vizuete, A. Villanueva, J. Ceron

This study investigates cisplatin sensitivity in C. elegans, identifying factors like DAF-16/FOXO, SKN-1/Nrf2, and the intrinsic apoptotic pathway, and discovers a resistance mechanism involving trxr-1 and selenocysteine.

bioRxiv · Dec 12, 2017Cancer Biology