Optimized dimerization of the PAR-2 RING domain drives cooperative and selective membrane recruitment for robust feedback-driven cell polarization
T. Bland, N. Hirani, D. Briggs, R. Rossetto, K. Ng, N. Q. McDonald, D. Zwicker, N. W. Goehring
This study shows that optimized dimerization of the PAR-2 RING domain enables cooperative and selective membrane recruitment, enhancing robustness and responsiveness in cell polarization.
bioRxiv · Aug 10, 2023 · PreprintCell Biology