D. Zwicker

Power-law growth models explain incidences and sizes of pancreatic cancer precursor lesions and confirm spatial genomic findings

The paper uses AI-based 3D tissue mapping to show PanIN lesion sizes follow a power-law distribution and identifies growth mechanisms driving pancreatic cancer precursor lesions.

Optimized dimerization of the PAR-2 RING domain drives cooperative and selective membrane recruitment for robust feedback-driven cell polarization

This study shows that optimized dimerization of the PAR-2 RING domain enables cooperative and selective membrane recruitment, enhancing robustness and responsiveness in cell polarization.

Crossover patterning through kinase-regulated condensation and coarsening of recombination nodules

The paper shows CDK-2 stabilizes crossover intermediates and pro-crossover factors in C. elegans, proposing a model of recombination nodule formation through condensation and coarsening.

Mechanisms of active regulation of biomolecular condensates

The paper proposes two mechanisms for active regulation of biomolecular condensates through post-translational modifications and tests them against known condensate types.