Lipin-1 restrains macrophage lipid synthesis to promote inflammation resolution.
T. T. Bamgbose, R. M. Schilke, O. O. Igiehon, E. H. Nkadi, D. Custis, S. Bharrhan, B. Schwarz, E. Bohrnsen, C. Bosio, R. S. Scott, A. Yurdagul, B. Finck, M. Woolard
This study shows that lipin-1 limits macrophage lipid synthesis, which supports inflammation resolution by enhancing efferocytosis.
bioRxiv · Oct 23, 2023Immunology