Arrest of mouse preterm labor until term delivery by combination therapy with atosiban and mundulone, a natural product with tocolytic efficacy
S. Siricilla, C. J. Hansen, J. H. Rogers, D. De, C. L. Simpson, A. G. Waterson, G. A. Sulikowski, S. L. Crockett, N. Boatwright, J. J. Reese, B. C. Paria, J. M. Newton, J. L. Herington
This study evaluates the tocolytic efficacy of mundulone and its analog MA, showing synergism with atosiban and demonstrating their potential to delay preterm labor in mice.
bioRxiv · Jun 6, 2023Pharmacology & Toxicology