Mebendazole for Differentiation Therapy of Acute Myeloid Leukemia Identified by a Lineage Maturation Index
Y. Li, D. Thomas, A. Deutzmann, R. Majeti, D. Felsher, D. Dill
This study identifies mebendazole as a potential differentiation therapy for AML using a novel computational method called LMI, showing it induces differentiation and improves survival in mouse models.
bioRxiv · Jul 1, 2019Cancer Biology