Probing the Modularity of Megasynthases by Rational Engineering of a Fatty Acid Synthase (FAS) Type I
A. Rittner, K. S. Paithankar, D. Drexler, A. Himmler, M. Grininger
This study re-engineers animal fatty acid synthase (FAS) to probe modularity in FAS/PKS family, creating new PKS-like modules with enhanced catalytic efficiency.
bioRxiv · Jul 27, 2018Biochemistry