Author

A. Rittner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:protein folding & dynamics· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:genetic perturbation / CRISPR· 1 Approach:statistical model· 1

Frequent Co-Authors

M. Grininger· 4 shared A. Himmler· 2 shared K. S. Paithankar· 2 shared B. Goebel· 1 shared C. S. Heil· 1 shared D. Beyer· 1 shared D. Drexler· 1 shared D. H. Sherman· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersBiochemistry

M. Grininger

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Directed biosynthesis of fluorinated polyketides

A. Rittner, M. Joppe, J. J. Schmidt, L. M. Mayer, E. Heid, D. H. Sherman, M. Grininger

This paper describes a method to directly fluorinate polyketides using a modified PKS enzyme, demonstrating its application in creating a fluorinated antibiotic derivative.

bioRxiv · Jul 30, 2021 · PreprintBiochemistry

Type I fatty acid synthase (FAS) trapped in the octanoyl-bound state

A. Rittner, K. S. Paithankar, A. Himmler, M. Grininger

The paper presents the crystal structure of murine FAS in an octanoyl-bound state, revealing structural dynamics and substrate specificity that inform inhibitor design.

bioRxiv · Aug 28, 2019Biochemistry

Probing the Modularity of Megasynthases by Rational Engineering of a Fatty Acid Synthase (FAS) Type I

A. Rittner, K. S. Paithankar, D. Drexler, A. Himmler, M. Grininger

This study re-engineers animal fatty acid synthase (FAS) to probe modularity in FAS/PKS family, creating new PKS-like modules with enhanced catalytic efficiency.

bioRxiv · Jul 27, 2018Biochemistry

Site-Specific Labelling of Multidomain Proteins by Amber Codon Suppression

C. S. Heil, A. Rittner, B. Goebel, D. Beyer, M. Grininger

The paper investigates the use of amber codon suppression to label multidomain proteins, demonstrating its applicability through a microplate-based assay and conformational analysis of murine fatty acid synthase.

bioRxiv · Mar 14, 2018Biochemistry