Author

A. Himmler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Rittner· 2 shared K. S. Paithankar· 2 shared M. Grininger· 2 shared D. Drexler· 1 shared

Activity by Year

2018-2019 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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2 shared papersBiochemistry

A. Rittner

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2 papers

Recent·Most cited

Type I fatty acid synthase (FAS) trapped in the octanoyl-bound state

A. Rittner, K. S. Paithankar, A. Himmler, M. Grininger

The paper presents the crystal structure of murine FAS in an octanoyl-bound state, revealing structural dynamics and substrate specificity that inform inhibitor design.

bioRxiv · Aug 28, 2019Biochemistry

Probing the Modularity of Megasynthases by Rational Engineering of a Fatty Acid Synthase (FAS) Type I

A. Rittner, K. S. Paithankar, D. Drexler, A. Himmler, M. Grininger

This study re-engineers animal fatty acid synthase (FAS) to probe modularity in FAS/PKS family, creating new PKS-like modules with enhanced catalytic efficiency.

bioRxiv · Jul 27, 2018Biochemistry