Small gene networks can delineate immune cell states and characterize immunotherapy response in melanoma
D. Egan, M. Kreileder, M. Nabhan, L. F. Iglesias-Martinez, S. Dovedi, V. Valge-Archer, A. Grover, R. Wilkinson, T. Slidel, C. Bendtsen, I. Barrett, D. Brennan, W. Kolch, V. Zhernovkov
This paper uses small transcription factor-directed co-expression networks to deconvolute immune cell states from bulk RNA-seq data and characterize immunotherapy response in melanoma.
bioRxiv · Jul 11, 2022Immunology