Author

W. Kolch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Krstic· 2 shared A. Blanco· 1 shared A. Grover· 1 shared A. McCann· 1 shared A. Neve· 1 shared B. McCann· 1 shared C. Bendtsen· 1 shared D. Brennan· 1 shared

Activity by Year

2022-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

A. Krstic

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Kinase Suppressor of RAS 1 (KSR1) maintains the transformed phenotype of BRAFV600E mutant human melanoma cells

Z. Liu, A. Krstic, A. Neve, N. Rauch, K. Wynne, H. Cassidy, A. McCann, E. Kavanagh, B. McCann, A. Blanco, J. Rauch, W. Kolch

This study shows that KSR1 is essential for maintaining the transformed phenotype of BRAFV600E mutant melanoma cells by promoting cell survival and inhibiting senescence and apoptosis.

bioRxiv · Aug 16, 2022Cancer Biology

Small gene networks can delineate immune cell states and characterize immunotherapy response in melanoma

D. Egan, M. Kreileder, M. Nabhan, L. F. Iglesias-Martinez, S. Dovedi, V. Valge-Archer, A. Grover, R. Wilkinson, T. Slidel, C. Bendtsen, I. Barrett, D. Brennan, W. Kolch, V. Zhernovkov

This paper uses small transcription factor-directed co-expression networks to deconvolute immune cell states from bulk RNA-seq data and characterize immunotherapy response in melanoma.

bioRxiv · Jul 11, 2022Immunology

Analysis of alternative mRNA splicing in vemurafenib-resistant melanoma cells

H. Bokharaie, W. Kolch, A. Krstic

The paper analyzes alternative mRNA splicing in vemurafenib-resistant melanoma cells and finds that combining multiple AS analysis tools improves accuracy and identifies biologically relevant splicing events.

bioRxiv · Mar 16, 2022Cancer Biology