Author

I. Barrett

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

A. Bender· 1 shared A. Grover· 1 shared A. Martinsson· 1 shared C. Bendtsen· 1 shared D. Brennan· 1 shared D. Egan· 1 shared E. Mouchet· 1 shared E. Mullers· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Bender

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Small gene networks can delineate immune cell states and characterize immunotherapy response in melanoma

D. Egan, M. Kreileder, M. Nabhan, L. F. Iglesias-Martinez, S. Dovedi, V. Valge-Archer, A. Grover, R. Wilkinson, T. Slidel, C. Bendtsen, I. Barrett, D. Brennan, W. Kolch, V. Zhernovkov

This paper uses small transcription factor-directed co-expression networks to deconvolute immune cell states from bulk RNA-seq data and characterize immunotherapy response in melanoma.

bioRxiv · Jul 11, 2022Immunology

Cell morphological profiling enables high-throughput screening for PROteolysis TArgeting Chimera (PROTAC) phenotypic signature

K. Moreau, M.-A. Trapotsi, E. Mouchet, G. Williams, T. Monteverde, K. Juhani, R. Turkki, F. Miljkovic, A. Martinsson, L. Mervin, E. Mullers, I. Barrett, O. Engkvist, A. Bender

This study uses cell morphological profiling to identify phenotypic signatures of PROTACs, revealing mitotoxicity that cannot be predicted from individual components.

bioRxiv · Jan 17, 2022Pharmacology & Toxicology