The human α-defensin-derived peptide HD5(1-9) inhibits cellular attachment and entry of human cytomegalovirus.
R. Böffert, R. Businger, H. Preiss, D. Ehmann, V. Truffault, C. Simon, N. Ruetalo, K. Hamprecht, P. Müller, J. Wehkamp, M. Schindler
The paper identifies HD5(1-9), a defensin-derived peptide, as an inhibitor of HCMV cellular attachment and entry, with low toxicity.
bioRxiv · Nov 5, 2019Microbiology