Author

R. Businger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1

Frequent Co-Authors

M. Schindler· 4 shared K. Hamprecht· 2 shared N. Ruetalo· 2 shared A. Dirlam· 1 shared A. N. R. Weber· 1 shared C. Simon· 1 shared D. Ehmann· 1 shared D. Stegner· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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4 shared papersMicrobiology

M. Schindler

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Abemaciclib restricts HCMV replication by suppressing pUL97-mediated phosphorylation of SAMHD1

G. Vavouras Syrigos, M. Feige, A. Dirlam, R. Businger, I. Gruska, L. Wiebusch, K. Hamprecht, M. Schindler

This study shows that Abemaciclib inhibits HCMV replication by blocking pUL97-mediated SAMHD1 phosphorylation, establishing SAMHD1 as a therapeutic target.

bioRxiv · Feb 1, 2023Microbiology

Rapid, dose-dependent and efficient inactivation of surface dried SARS-CoV-2 by 254 nm UV-C irradiation

N. Ruetalo, R. Businger, M. Schindler

This study evaluates the effectiveness of 254 nm UV-C irradiation in inactivating surface-dried SARS-CoV-2, showing dose-dependent inactivation and a non-linear relationship between UV-C dose and viral titer reduction.

bioRxiv · Sep 22, 2020Microbiology

The human α-defensin-derived peptide HD5(1-9) inhibits cellular attachment and entry of human cytomegalovirus.

R. Böffert, R. Businger, H. Preiss, D. Ehmann, V. Truffault, C. Simon, N. Ruetalo, K. Hamprecht, P. Müller, J. Wehkamp, M. Schindler

The paper identifies HD5(1-9), a defensin-derived peptide, as an inhibitor of HCMV cellular attachment and entry, with low toxicity.

bioRxiv · Nov 5, 2019Microbiology

Platelet-neutrophil aggregates promote skin pathology in psoriasis

F. Herster, Z. Bittner, M. C. Codrea, N. Archer, M. Heister, M. W. Loeffler, S. Heumos, J. Wegner, R. Businger, M. Schindler, D. Stegner, K. Schaekel, S. Grabbe, K. Ghoreschi, L. Miller, A. N. R. Weber

This study identifies platelet-neutrophil aggregates as contributors to psoriasis skin pathology and disease severity.

bioRxiv · Jan 28, 2019 · PreprintImmunology