Author

D. F. Claxton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. Sharma· 1 shared B. J. Horton· 1 shared C. E. Chalfant· 1 shared D. J. Feith· 1 shared H.-G. Wang· 1 shared J. J. Shaw· 1 shared J. Ung· 1 shared M. C. Cabot· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Sharma

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1 paper

Recent·Most cited

Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia

J. Ung, S.-F. Tan, T. E. Fox, J. J. Shaw, M. Taori, B. J. Horton, U. Golla, A. Sharma, Z. M. Szulc, H.-G. Wang, C. E. Chalfant, M. C. Cabot, D. F. Claxton, T. P. Loughran, D. J. Feith

This study evaluates the anti-leukemic effects of LCL-805, an acid ceramidase inhibitor, in AML cell lines and patient samples, showing it promotes iron-dependent cell death by antagonizing Akt signaling.

bioRxiv · Oct 21, 2023Cancer Biology