Author

D. Flament

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Assay:cryo-EM· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

A. C. Alberti· 1 shared A. Haouz· 1 shared B. Raynal· 1 shared C. Madru· 1 shared C. Mottez· 1 shared C. Ryan· 1 shared E. Leroy· 1 shared E. Roussel· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperBiochemistry

A. C. Alberti

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Structuring effects of archaeal replication origins

C. Mottez, R. Puech, D. Flament, H. Myllykallio

This study shows archaeal replication origins prevent replication-transcription conflicts and coordinate genetic information transfer, suggesting roles beyond DNA replication initiation.

bioRxiv · Nov 15, 2023 · PreprintMicrobiology

DNA-binding mechanism and evolution of Replication Protein A

C. Madru, M. Martinez-Carranza, S. Laurent, A. C. Alberti, M. Chevreuil, B. Raynal, A. Haouz, R. A. Le Meur, M. Delarue, D. Flament, M. Krupovic, P. Legrand, L. Sauguet

This study characterizes the DNA-binding mechanism of RPA from Pyrococcus abyssi using crystal and cryo-EM structures, revealing conserved features and a novel archaeal-specific domain.

bioRxiv · Jul 20, 2022Biochemistry

Role of Ori in Thermococcus barophilus

Y. Moalic, C. Ryan, E. Leroy, L. Mc Teer, V. Cueff-Gauchard, J. Aube, Y. Lu, E. Roussel, J. Oberto, D. Flament, R. Dulermo

This study investigates the role of the origin of replication (Ori) in Thermococcus barophilus, showing its necessity for DNA replication and growth under varying temperatures.

bioRxiv · Apr 27, 2021 · PreprintMicrobiology